A/A: antibiotic-antimycotic
aHSIL: anal high grade squamous intraepithelial lesion
ANCHOR: anal cancer HSIL (high grade squamous intraepithelial lesion) outcomes research
BLAST: basic local alignment search tool
BSC: biological safety cabinet
BSL: biosafety level
CDC: Center for Disease Control and Prevention
cDNA: complementary DNA
CAP: College of American Pathologists
CAPA: corrective and preventive action
ccfDNA: cell-free DNA
CIA: chemiluminescent Immunoassay
CIN: cervical intraepithelial neoplasia
CIN2+: cervical intraepithelial neoplasia grade 2 or higher
CP: control positive
CPD: continued professional development
Cq: cycle validation
CsCl: caesium chloride
Ct: cycle threshold
CV: coefficient of variance
DAMA: Data management association
DEPC: diethylpyrocarbonate
DBPS: Duulbecco´s phosphate buffered saline
DMEM-PF: phenol red-free Dulbecco’s modified Eagle Medium
DNA: deoxyribonucleic acid
dNTPs: deoxynucleoside triphosphates
dPCR: digital PCR
dsDNA: double stranded DNA
ECBS: Expert Committee on Biological Standardization
EDTA: ethylene-diamine-tetra-acetic acid E1-E7 early proteins of HPV numbered E1–E7 (however no E3)
EIA: enzyme immunoassay
ELISA: enzyme-linked immunosorbent assay
ENC: extraction negative congrol
EQA: external quality assessment
eWGS: enriched whole gnome sequencing
FBS: fetal bovine serum
FFPE: formalin fixed paraffin embedded
GE: genome equivalents
GLUT: Glutamax I
HBV: hepatitis B virus
HC2: hybrid capture 2 (Digene®, Qiagen)
HCV: hepatitis C virus
H&E: hematoxylin and eosin
HIV: human immunodeficiency virus
HPV: human papillomavirus
HPV: LabNet Global network of national HPV reference laboratories
HPVRG: human papillomavirus research group
HR: high risk
HRP: horseradish peroxidase
HSIL: high grade squamous intraepithelial lesion
IARC: International Agency for Research on Cancer
IATA: International Aviation and Transportation Administration
ICH: International Committee on Harmonization
ICTV: International Committee on Taxonomy of Viruses
ID: identification
Ig: immunoglobulin
IgG: immunoglobulin G
ILS: interlaboratory schemes
IHRC: International HPV Reference Center
IQC: internal quality control
IRB: internal review board
IS: international standard
iSNVs: intrahost single nucleotide variants
IT information technology
IU: international unit
IVD: in vitro diagnostic medical device
IVDR: in vitro diagnostic medical device regulation
kDa: kilodalton
L: litre
L1, L2: late proteins of HPV, major (L1) and minor (L2) proteins of capsid lab laboratory
LAMP: loop-mediated isothermal amplification
LBC: liquid based cytology
LDT: laboratory developed test
LIMS: laboratory information systems
LQA: laboratory quality assurance
LR: low risk
LSIL: low grade squamous intraepithelial lesion
M: molar
mg: milligram
MGP: modified general primers
min: minute
MiQE: minimum information for publication of quantitative real-time PCR
mL: millilitre
mM: millimetre
MSD: meso scale discovery
uL: microlitre
mRNA: messenger RNA
MS mass spectrometry
MSDS: material safety data sheet
NCBI: National Center for Biotechnology Information
NEAA: non-essential amino acids
NGS :next generation sequencing
NIBSC: National Institute for Biological Standards and Control
NIH: National Institutes of Health
nm: nanometer (10-9 metre)
NRL: national reference laboratory
NTC: no template control
OD: optical density
ORF: open reading frame
PBS: phosphate buffered saline
PAHO: panamerican health organization
PAVE: Papillomavirus Episteme
PCR: polymerase chain reaction
PDCA: Plan-Do-Check act
pg: picogram
PLL: parallel line
PsV: pseudovirion
QA: quality assurance
QC: quality control
QMS: quality management system
qPCR: real time PCR
RNA: ribonucleic acid
RPA: recombinase polymerase amplification
rtPCR: reverse transtription RCR
SD: standard deviation
SHPVRL: Scottish HPV reference laboratory
SOP: standard operating procedure
SPF: short PCR fragment
STM: specimen transport media (Qiagen)
TameSeq: tagmentation assisted multiplex PCR enrichment sequencing
TBE: (buffer) Tris Borate EDTA
TE: (buffer) Tris EDTA
Tm: melting temperature
UN: United Nations
VALGENT: validation of HPV genotyping tests
VLP: virus-like particle
WHO: World Health Organization